Fig. 5

Construction of the immune age prediction model (a) The prediction results of the random forest prediction model in the training set (top) and the test set (bottom). The Pearson correlation coefficient (R²) was utilized to quantify the relationship between the predicted age and the actual age (b) Violin chart showing the age prediction of monocytes in healthy controls and patients with mild or severe COVID-19 in the GSE206283 dataset at first admission. One-way ANOVA was used to calculate the difference between the groups (c) Bar chart showing the age prediction of monocytes in healthy controls and patients with mild or severe COVID-19 at first admission. An independent t test was used to calculate the differences between the groups (d) Violin plot showing the difference between the predicted age of monocytes and the actual age at first admission to the hospital in healthy controls and patients with mild or severe COVID-19. One-way ANOVA was used to calculate differences between groups (e) The bar chart shows the difference between the predicted age of monocytes and the actual age of healthy controls and mild or patients with severe COVID-19 when they were first admitted. The difference between groups was calculated using independent t tests