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Fig. 2 | Immunity & Ageing

Fig. 2

From: The immunological age prediction of monocytes indicates that gestational diabetes mellitus accelerates the aging of monocytes in offspring

Fig. 2

Transcriptional characteristics of subclusters present within monocytes (a) UMAP plot showing the clusters of all monocytes (b) Dot plot showing the characteristic genes of each monocyte cluster (c) Violin diagram showing the expression of CD14 and FCGR3A (CD16) in each monocyte cluster (d) Heatmaps showing pathway enrichment results for each monocyte cluster. The colors represent the AUCell score (e) KEGG enrichment demonstrated the upregulation of the IL8 signaling pathway in c8 (f) The ability of CytoTrace to infer the level of cell differentiation is demonstrated through a boxplot, which illustrates the anticipated degree of differentiation within each group of monocytes (g) Left: CytoTrace was utilized on the left to forecast the cell cycle distribution, with colors indicating the anticipated level of differentiation. The UMAP diagram was used to visualize the anticipated cellular localization based on the differentiation level. Right: The diagram illustrates the distribution of distinct clusters within the UMAP diagram

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Immunity & Ageing

ISSN: 1742-4933

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