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Table 1 Characteristics of adults in National Health and Nutrition Examination Survey 2003–2006 and 2009–2010

From: The relationship between biological aging and psoriasis: evidence from three observational studies

Variables

Non-psoriasis, n = 12,630 (weighted& % = 96.88)

Psoriasis, n = 343 (weighted& % = 3.12)

p-value

Gender

  

0.786

 Male

6060 (48.8)

163 (49.6)

 

 Female

6570 (51.2)

180 (50.4)

 

Age

41.50 ± 14.67

44.30 ± 14.11

 < 0.001**

Race/ethnicity

  

 < 0.001**

 Mexican American

2570 (9.3)

33 (3.5)

 

 Other Hispanic

896 (4.5)

21 (2.9)

 

 Non-Hispanic White

5836 (67.7)

230 (82.4)

 

 Non-Hispanic Black

2664 (12.1)

44 (6.7)

 

 Other Race—Including Multi-Racial

664 (6.4)

15 (4.5)

 

Education

  

0.694

 Did not graduate high school

3141 (16.6)

71 (14.8)

 

 High school graduate

3314 (25.1)

84 (23.2)

 

 Did not graduate college

3731 (32.6)

107 (35.0)

 

 College graduate

2444 (25.7)

81 (26.9)

 

Annual household income

  

0.821

 < $20,000

2480 (13.5)

77 (13.9)

 

 ≥ $20,000

10,150 (86.5)

266 (86.1)

 

BMI

28.41 ± 6.71

29.99 ± 7.07

 < 0.001**

Smoking

  

 < 0.001**

 Yes

5520 (45.4)

202 (59.6)

 

 No

7110 (55.6)

141 (40.4)

 

Drinking

  

0.345

 Yes

9291 (78.0)

270 (80.8)

 

 No

3339 (22.0)

73 (19.2)

 

Average physical activity level

  

0.679

 Vigorous work activity

2837 (24.7)

80 (26.1)

 

 Moderate to low intensity work activities

9793 (75.3)

263 (73.9)

 

Diabetes

  

0.446

 Yes

1210 (7.6)

42 (8.9)

 

 No

11,420 (92.4)

301 (91.1)

 

Hypertension

  

0.001**

 Yes

3302 (23.9)

134 (34.1)

 

 No

9328 (76.1)

209 (65.9)

 

Kidney disease

  

0.147

 Yes

261 (1.5)

11 (2.6)

 

 No

12,369 (98.5)

332 (97.4)

 

Liver disease

  

0.336

 Yes

373 (3.0)

16 (3.8)

 

 No

12,257 (97.0)

327 (96.2)

 

Thyroid disease

  

0.456

 Yes

960 (8.4)

34 (9.9)

 

 No

11,670 (91.6)

309 (90.1)

 

Heart disease,

  

0.005**

 Yes

630 (4.0)

40 (7.2)

 

 No

12,000 (96.0)

303 (92.8)

 

Cancer

  

 < 0.001**

 Yes

786 (6.4)

45 (12.7)

 

 No

11,844 (93.6)

298 (87.3)

 

Systolic blood pressure (mmHg)

119.75 ± 15.57

120.84 ± 15.65

0.157

Albumin (g/dL)

4.28 ± 0.34

4.23 ± 0.35

0.023*

Alkaline phosphatase (U/L)

67.66 ± 22.59

68.76 ± 22.80

0.352

Total cholesterol (mg/dL)

197.44 ± 41.33

201.40 ± 40.43

0.118

Serum glucose (mg/dL)

5.30 ± 1.60

5.26 ± 1.38

0.690

Creatinine (mg/dL)

0.88 ± 0.30

0.90 ± 0.18

0.073

Blood urea nitrogen (mg/dL)

12.19 ± 4.64

12.73 ± 4.99

0.019*

Uric acid (mg/dL)

5.35 ± 1.37

5.46 ± 1.34

0.121

C-reactive protein (mg/dL)

0.38 ± 0.75

0.47 ± 0.92

0.112

Glycohemoglobin (%)

5.47 ± 0.82

5.48 ± 0.77

0.831

White blood cell count (1000 cells/uL)

7.29 ± 2.14

7.43 ± 2.05

0.204

Lymphocyte (%)

30.38 ± 7.83

29.09 ± 7.67

0.017*

Red cell distribution width (%)

12.66 ± 1.08

12.86 ± 1.24

0.004**

Mean cell volume (fL)

89.81 ± 5.20

90.19 ± 5.84

0.329

DII

0.97 ± 1.51

0.93 ± 1.55

0.717

PhenoAge

41.06 ± 15.18

44.64 ± 14.99

 < 0.001**

PhenoAge advance

-0.44 ± 4.38

0.34 ± 4.83

0.001**

PhenoAge advance acceleration

  

 < 0.001**

 Yes

5271 (37.0)

173 (46.6)

 

 No

7359 (63.0)

170 (53.4)

 

KDM-Age

39.28 ± 15.26

42.23 ± 14.52

 < 0.001**

KDM-Age advance

-2.22 ± 8.64

-2.08 ± 7.58

0.754

KDM-Age advance acceleration

  

0.280

 Yes

4766 (34.7)

129 (38.0)

 

 No

7866 (65.3)

214 (62.0)

 
  1. Values that are statistically significant (two-side P value < 0.05) are indicated by *; Values that are statistically significant (two-side P value < 0.01) are indicated by **; BMI Body mass index (calculated as kg/m2); NHANES National Health and Nutrition Examination Survey; &Weighted percentage was calculated using NHANES survey design parameters, DII Dietary inflammation index, HEI2015 Healthy eating index, KDM-Age Klemera-Doubal method age