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Table 3 Logistic regression of MetS (Non-met as reference group) and components of MetS with prevalence of Frailty at baselines (N = 11,552)

From: The association of multidimensional frailty with metabolic syndrome and low-grade inflammation in community-dwelling older adults in the Netherlands: a Lifelines cohort study

Ā 

Model 1

Model 2

Model 3

Model 4

Ā 

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

OR

95% CI

p

MetS

1.5

1.34–1.67

< 0.001

1.47

1.31–1.65

< 0.001

1.40

1.25–1.57

< 0.001

1.37

1.22–1.53

< 0.001

Components of MetS

Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā Ā 

Abdominal obesity (Europids)

1.18

1.03–1.36

0.02

1.16

1.00-1.33

0.04

1.10

0.95–1.27

0.2

1.09

0.95–1.26

0.2

ā€ƒRaised TG

1.29

1.13–1.47

< 0.001

1.26

1.11–1.44

0.001

1.20

1.05–1.37

0.006

1.19

1.04–1.36

0.01

ā€ƒReduced HDL-C

1.37

1.19–1.57

< 0.001

1.36

1.18–1.57

< 0.001

1.29

1.11–1.48

0.001

1.26

1.09–1.46

0.001

ā€ƒElevated BP

1.57

1.41–1.74

< 0.001

1.57

1.41–1.74

< 0.001

1.54

1.38–1.72

< 0.001

1.50

1.35–1.68

< 0.001

ā€ƒRaised FPG

1.33

1.19–1.49

< 0.001

1.28

1.15–1.44

< 0.001

1.24

1.11–1.40

< 0.001

1.23

1.10–1.38

< 0.001

  1. * Model 1 adjusted for age, sex; model 2, model 1 adjusted for education and living alone; model 3, model 2 adjusted for smoking status, MVPA < 150Ā min/week, sleep duration, alcohol consumption, and LLDS; model 4, model 3 adjusted for presence of presence of stroke, cancer, CKD, and lung diseases
  2. † MetS: metabolic syndrome; OR: odds ratio; CI: confidence interval; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; BP: blood pressure; FPG: fasting plasma glucose; MVPA: Non-occupational moderate-to-vigorous physical activity; LLDS: Lifelines diet score; CKD: chronic kidney disease