Fig. 2

Shows that aging disrupts the typical process of adipogenesis, causing dysfunction in BAT, WAT, and beige adipocytes. This disruption is characterized by disturbances in endocrine secretions, reduced mitochondrial biogenesis, and decreased sympathetic tone within adipose tissues. These factors contribute to hypertrophy and the accumulation of dead cells, increasing the release of proinflammatory adipokines and the buildup of visceral fat and inflammation