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Fig. 1 | Immunity & Ageing

Fig. 1

From: Melatonin enhances NK cell function in aged mice by increasing T-bet expression via the JAK3-STAT5 signaling pathway

Fig. 1

Melatonin treatment enhances the expression of CD107a and the secretion of IFN-γ in NK cells. (A) NK cells were isolated from mouse spleen, subjected to in vitro melatonin treatment, and subsequently stimulated with RMA-S cells to assess the NK cells’ capability to secrete CD107a. (B) Statistical chart representing CD107a secretion by NK cells. (C) Isolating NK cells from mouse spleens, subjecting them to in vitro melatonin treatment, and then stimulating them with RMA-S cells to assess the NK cells’ potential to secrete IFN-γ. (D) Statistical chart depicting IFN-γ secretion by NK Cells. The data is presented as means ± SD. n = 6. Statistical analysis was performed using Prism software with one-way ANOVA. A significance level of < 0.05 was deemed as statistically significant. *P < 0.05

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Immunity & Ageing

ISSN: 1742-4933

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