Fig. 6

Ccrl2 is specifically upregulated in female AD temporal cortex. (a) The expression level of Ccrl2 in temporal cortex (TC) of female AD patients (n = 14) was significantly higher (p = 0.017) than healthy humans (n = 18). (b) The expression level of Ccrl2 in entorhinal cortex (EC) of female AD patients (n = 18) and healthy humans (n = 15). (c) The expression level of Ccrl2 in frontal cortex (FC) of female AD patients (n = 30) and healthy humans (n = 34). Data are shown as mean ± SEM and two-tailed, unpaired Student’s t-test was used. *p < 0.05