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Table 2 Cross-Sectional Associations between the NLR and CSF Outcomes in the ADNI and NYU Cohorts

From: The neutrophil to lymphocyte ratio associates with markers of Alzheimer’s disease pathology in cognitively unimpaired elderly people

 

Univariate Model

Adjusted Model

Cohort

CSF Outcome

NLR β ± SE

NLR p-value

NLR β ± SE

NLR p-value

ADNI

Aβ42

-11.623 ± 5.236

0.029

-12.193 ± 5.185

0.021

t-tau

5.126 ± 3.184

0.110

3.924 ± 3.247

0.230

p-tau

2.602 ± 2.028

0.202

2.464 ± 2.029

0.227

NYU

Aβ42

24.979 ± 19.373

0.199

19.109 ± 19.555

0.330

t-tau

45.698 ± 17.799

 < 0.001

26.812 ± 11.370

0.019

p-tau

5.211 ± 1.397

 < 0.001

3.441 ± 1.404

0.015

  1. Unadjusted and adjusted linear regression models for the association of the NLR and the three outcome variables are shown (Aβ42, t-tau, p-tau). Adjusted models included age, sex, education, race, APOE4, time between CBC and CSF exams, BMI, history of hypertension, and diabetes. β coefficients, standard errors, and p-values are shown
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Immunity & Ageing

ISSN: 1742-4933

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