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Fig. 1 | Immunity & Ageing

Fig. 1

From: Hindlimb unloading, a physiological model of microgravity, modifies the murine bone marrow IgM repertoire in a similar manner as aging but less strongly

Fig. 1

Evaluation of stress in HU and aged mice. A Corticosterone concentrations in sera, determined by ELISA, in control vs. HU (n = 10 in each group) and young vs. aged mice (n = 19 in each group). B Quantification, by quantitative real-time PCR, of NR3C1 mRNAs in the bone marrow of control vs. HU (n = 24 in each group) and young vs. aged mice (n = 27 in each group). This transcript encodes the glucocorticoid receptor. mRNA levels were normalized to those of 3 housekeeping transcripts. The relative value obtained with controls or young mice was set to 1. Data are shown as the means ± SDs. Statistically significant differences were found using Mann–Whitney or unpaired t tests. ***p ≤ 0.001

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Immunity & Ageing

ISSN: 1742-4933

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