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Fig. 7 | Immunity & Ageing

Fig. 7

From: Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions

Fig. 7

The effect of VCAM-1 on BMDM activation and macrophage-to-myofibroblast transition. BMDM were treated with or without different concentrations of recombinant murine VCAM-1 protein (100, 500, and 1000 ng/ml) for 24 h. The expression of iNOS, Il1b, Il6, Arg1, Mmp12, Il10, Col1a1, Fn1 and Acta2 was examined by RT-qPCR. Mean ± SD, n = 6, *P < 0.05, **P < 0.01, ***P < 0.001. One-way ANOVA followed by Dunnett's test

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Immunity & Ageing

ISSN: 1742-4933

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