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Table 6 Ratios of pre-vaccination HAI antibody titers measured using current season vaccine strain antigens over those using prior season vaccine strain antigens among individuals who participated in respective two consecutive study seasonsa

From: Interseason waning of vaccine-induced hemagglutination inhibition antibody titers and contributing factors to pre-existing humoral immunity against influenza in community-dwelling older adults 75 years and older

Vaccine strain

Individual study season

Unadjusted

Adjustedb

IAV H3N2

2015 (n = 49)

0.39 (0.32–0.47) (p < .01)

0.36 (0.36–0.50) (p < .01)

2016 (n = 52)

0.64 (0.50–0.81) (p < .01)

0.56 (0.33–0.94) (p = .03)

IBV

2015 (n = 49)

0.48 (0.41–0.55) (p < .01)

0.41 (0.32–0.51) (p < .01)

2016 (n = 52)

1.77 (1.32–2.37) (p < .01)

0.84 (0.47–1.49) (p = .55)

IAV H1N1

2017 (n = 78)

0.86 (0.79–0.94) (p < .01)

0.86 (0.75–0.99) (p = .04)

  1. aRatios of pre-vaccination HAI titers measured using current study season vaccine strain antigens over those measured using prior season vaccine strain antigens among individuals who participated in the same two consecutive study seasons as the main analysis
  2. bAdjusted for age at the study season, sex, race, and education
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Immunity & Ageing

ISSN: 1742-4933

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