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Table 5 Interseason antibody waning estimated using current season vaccine strain antigensa

From: Interseason waning of vaccine-induced hemagglutination inhibition antibody titers and contributing factors to pre-existing humoral immunity against influenza in community-dwelling older adults 75 years and older

Vaccine strain

Consecutive two seasons

Unadjusted

Adjustedb

IAV-H3N2

2014–2015 (n = 49)

0.27 (0.20–0.36) (p < .01)

0.25 (0.14–0.44) (p < .01)

2015–2016 (n = 52)

0.25 (0.20–0.33) (p < .01)

0.21 (0.12–0.35) (p < .01)

IBV

2014–2015 (n = 49)

0.18 (0.15–0.22) (p < .01)

0.17 (0.12–0.24) (p < .01)

2015–2016 (n = 52)

0.96 (0.74–1.24) (p = .74)

0.67 (0.40–1.12) (p = .12)

IAV-H1N1

2016–2017 (n = 78)

0.58 (0.50–0.68) (p < .01)

0.59 (0.45–0.77) (p < .01)

  1. aRatios of pre-vaccination HAI antibody titers measured using current season vaccine strain antigens over prior season post-vaccination HAI titers measured using prior season vaccine strain antigens among participants who completed the study in the two consecutive study seasons
  2. bAdjusted for age at prior study season, sex, race, and education
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Immunity & Ageing

ISSN: 1742-4933

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