Fig. 3
From: Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals

Four of the circRNA candidates are found to be upregulated in frail individuals assessed by qPCR. All the 35 frail and 35 robust individuals were studied separately during this validation. T-test or Wilcoxon rank sum tests were performed for the statistical analysis of normally and non-normally distributed variables, respectively. Note that a higher DCq value corresponds to a lower expression of the circRNA. Abbreviations and symbols: n.s., not significant; *, p-value ≤ 0.05;**, p-value ≤ 0.01; ****, p-value ≤ 0.0001