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Fig. 3 | Immunity & Ageing

Fig. 3

From: 12-week combined strength and endurance exercise attenuates CD8+ T-cell differentiation and affects the kynurenine pathway in the elderly: a randomized controlled trial

Fig. 3

A Flow cytometric gating strategy for the analysis of T-cell subsets B Absolute changes in proportions of peripheral CD8+ T-cell subsets per study group over the twelve-week intervention period (Δ = t12—t0). *(p < .05) indicates a significant difference between groups, analysed using rmANCOVA. C Absolute changes of plasma metabolites of the KYN pathway in µmol/L (Δ = t12—t0). *(p < .05) indicates a significant difference between groups, analysed using rmANCOVA. CON = control group; EX (two-group-comparison) = exercise group (with and without nutrition instructions); EX (three-group-comparison) = exercise group without nutrition instructions; EX + NUTR = exercise group with nutrition instructions; EMRA CD8 +  = Effector Memory re-expressing CD45RA CD8 + cells; TRP = tryptophane, KYN = kynurenine; QA = quinolinic acid; KA = kynurenic acid

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Immunity & Ageing

ISSN: 1742-4933

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