Fig. 3

CMV serostatus modifies the association between biological aging (BA) and antibody responses in high dose recipients. The correlation between standardized ΔBA and 4-week antibody titre was estimated using mixed model regression, adjusting for the fixed effect of baseline titre and other covariates. Shown in plot is the estimated marginal mean of the exponentiated log 4-week titre and 95% confidence interval (CI) across the range of standardized BA for CMV negative (red, dashed line) and positive (blue, solid line) participants, stratified by vaccine dose. The standardized coefficient and 95% CI for the log 4-week titre is shown in each panel for CMV(-) and CMV(+) participants, and significance at p < 0.05 indicated with an asterisk