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Table 3 The numbers of CD4+ and CD8+ T-cell subsets in peripheral blood before and after the 12-week intervention. N=naïve, CM=central memory, EM=effector memory, EMRA= CD45RA+ Effector Memory, RTE=recent thymic emigrants. Data are mean (SD) with bolded p-values indicating p<0.05

From: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial

T-cell Subset

  

Pre (cells/µl WB)

Post (cells/µl WB)

p

|Hedge’s g|

CD4+

Naïve

HIIT*

264.03 (133.13)

163.46 (79.56)

0.02

0.87

  

MICT

148.70 (94.68)

178.94 (109.27)

0.17

0.28

  

UC

190.23 (97.01)

177.37 (131.75)

0.6

0.1

 

CD4 Naïve CD31+ (RTE)

HIIT*

227.36 (105.46)

142.48 (62.28)

0.01

0.93

  

MICT

134.54 (86.43)

154.74 (95.08)

0.3

0.21

  

UC

172.14 (90.48)

158.42 (123.98)

0.55

0.12

 

CM

HIIT

225.62 (76.13)

173.93 (59.4)

0.07

0.72

  

MICT

223.88 (107.66)

287.67 (134.81)

0.01

0.49

  

UC

270.94 (176.45)

224.46 (178.24)

0.3

0.25

 

EM

HIIT

191.09 (68.62)

132.26 (77.17)

0.05

0.76

  

MICT

189.59 (90.57)

194.86 (90.08)

0.82

0.06

  

UC

240.05 (161.12)

171.61 (119.61)

0.22

0.45

 

EMRA

HIIT

39.71 (39.04)

22.26 (16.32)

0.28

0.55

  

MICT

20.65 (12.36)

19.35 (10.55)

0.73

0.11

  

UC

27.82 (20.55)

26.56 (21.02)

0.66

0.06

CD8+

Naïve

HIIT

98.83 (68.05)

95.93 (51.65)

0.87

0.05

  

MICT

70.52 (68.04)

77.63 (49.88)

0.63

0.11

  

UC

109.05 (112.75)

114.4 (98.08)

0.84

0.05

 

CD8 Naïve CD103+ (RTE)

HIIT

1.87 (1.34)

6.46 (10.26)

0.22

0.59

  

MICT

1.04 (0.43)

0.95 (0.49)

0.49

0.2

  

UC

4.55 (4.96)

2.78 (3.38)

0.41

0.39

 

CM

HIIT

37.31 (20.55)

44.46 (24.35)

0.6

0.3

  

MICT

32.69 (20.5)

41.93 (16.85)

0.19

0.47

  

UC

38.94 (21.15)

37.56 (30.14)

0.91

0.04

 

EM

HIIT

93.01 (49.08)

74.95 (31.71)

0.1

0.26

  

MICT*

65.78 (40.84)

82.29 (45.1)

0.03

0.38

  

UC

98.29 (92.73)

87.16 (76.22)

0.57

0.31

 

EMRA

HIIT

44.84 (40.85)

41.53 (45.96)

0.63

0.07

  

MICT

24.28 (18.12)

23.29 (12.44)

0.67

0.06

  

UC

49.74 (42.38)

55.74 (71.31)

0.82

0.1