Skip to main content
Fig 1 | Immunity & Ageing

Fig 1

From: An evaluation of the recognised systemic inflammatory biomarkers of chronic sub-optimal inflammation provides evidence for inflammageing (IFA) during multiple sclerosis (MS)

Fig 1

Loss of immune tolerance in an ageing immune system. T cells /B cells in primary lymphoid organs plus peripheral T cells express tolerance checkpoint proteins . Biological ageing-associated ISC causes a decline in immune tolerance. Self-reactive immune cells develop and recruit inflammatory cells . Tissue-dependent autoimmune reactions and destructive mechanisms evolve

Back to article page

Immunity & Ageing

ISSN: 1742-4933

Contact us