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Table 4 Effects of BMI on immunosenescence in multivariable-adjusted regression models

From: Emergence of T cell immunosenescence in diabetic chronic kidney disease

 

Model 1

Adjusted for Age, Sex

Model 2

Adjusted for Age, Sex, CKD status

 

ß

p value

ß

p value

CD4+ TNAIVE (%)

−0.13

0.36

−0.19

0.20

CD4+ TEFF (%)

0.0062

0.82

0.0081

0.77

CD4+ CD127+ (%)

−0.056

0.26

−0.038

0.44

CD4+ CD28- (%)

0.082

0.19

0.073

0.25

CD4+ CD57+ (%)

0.027

0.48

0.023

0.56

CD8+ TNAIVE (%)

−0.20

0.083

−0.17

0.15

CD8+ TEFF (%)

0.25

0.17

0.20

0.28

CD8+ CD127+ (%)

−0.25

0.12

−0.19

0.23

CD8+ CD28- (%)

0.37

0.033*

0.30

0.087

CD8+ CD57+ (%)

0.42

0.0049*

0.37

0.017*

  1. Multivariable regression models to test the independent associations between immune profile and BMI. *: P value < 0.05. BMI: Body Mass Index. Monocyte 1: classical monocytes. Monocyte 2: intermediate monocytes. Monocyte 3: non-classical monocyte