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Fig. 1 | Immunity & Ageing

Fig. 1

From: Human MDSCs derived from the bone marrow maintain their functional ability but have a reduced frequency of induction in the elderly compared to pediatric donors

Fig. 1

Human MDSCs are induced from BM precursors of pediatric and elderly donors by growth factors. a Representative flow cytometry with CD11b and CD16 on BM cells before (left panels) and after (right panels) 4 days of cell culture with growth factors G-CSF and GM-CSF. Upper panels, pediatric BM cells; bottom panels, BM from elderly donors. b Percentage of the different myeloid differentiating subsets among BM cells (n = 4 independent experiments) or BM cultures (n = 20 independent experiments) for pediatric patients (upper panel), and percentage of the different myeloid differentiating subsets among BM cells (n = 14) or BM cultures (n = 18) for elderly patients (bottom panel). c Percentage of the different myeloid differentiating subsets after four days of cell culture with growth factors between pediatric and elderly donors. Mann-Whitney U test was performed according to data distribution

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Immunity & Ageing

ISSN: 1742-4933

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