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Table 2 Mean levels of inflammatory markers and complement pathway components in young and old adults

From: Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults

 

Young*

Old *

P-value

CRP (mg/L)

2.37 (2.16)

2.60 (1.91)

0.671

IL-6 (pg/ml)

1.59 (1.10)

2.46 (1.44)

0.013

TNF-α (pg/ml)

1.02 (0.266)

1.26 (0.42)

0.013

CH50 (U/mL)

69.13 (16.25)

74.10 (15.86)

0.249

C1q (units/ml)

722.7 (84.3)

651.4 (82.1)

0.002

C3 (mg/dL)

131.8 (22.3)

121.1 (26.1)

0.102

C4 (mg/dL)

27.40 (8.62)

25.70 (6.92)

0.420

MBL (ng/ml)

1650 (1251)

1889 (1541)

0.520

MBL (% activity)

45.37 (39.41)

53.78 (39.23)

0.424

CL-L1 (ng/ml)

486.2 (71.8)

482.8 (80.6)

0.866

MASP-1 (ng/ml)

12,117 (2838)

11,539 (3492)

0.493

MASP-2 (ng/ml)

600.1 (366.2)

507.6 (171.8)

0.236

MASP-3 (ng/ml)

7184 (1943)

7481 (2097)

0.580

MAp 44 (ng/ml)

2127 (519)

2166 (423)

0.758

MAp 19 (ng/ml)

372.6 (85.2)

360.1 (96.4)

0.604

H-ficolin (ng/ml)

24,091 (9085)

27,370 (5889)

0.116

M-ficolin (ng/ml)

3500 (1195)

3813 (1056)

0.304

L-ficolin (ng/ml)

3044 (1403)

3314 (995)

0.403

  1. *Mean (standard deviation)