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Table 4 Percentage of individuals with HBsAg specific responses (cytokine production) in Junior and Senior groups

From: The SENIEUR protocol and the efficacy of hepatitis B vaccination in healthy elderly persons by age, gender, and vaccine route

 

Subsets

IFN-γ

TNF-α

IL-5

IL-4

IL-2

Totala

Respb

(%)

Totala

Respb

(%)

Totala

Respb

(%)

Totala

Respb

(%)

Totala

Respb

(%)

Juniors

9

9

100

11

8

73

11

10

91

11

9

82

11

9

82

Seniors

47

29

62

50

15

30

50

17

34

50

17

34

50

15

30

Seniors

IM

25

18

72

26

7

27

26

7

27

26

7

27

26

6

23

SC

21

11

52

23

8

35

23

10

43

23

10

43

23

9

39

Seniors

Female

25

16

64

27

10

37

27

8

30

27

8

30

27

9

33

Male

21

13

62

23

6

26

23

9

39

23

9

39

23

6

26

Seniors

65–74

34

22

65

37

13

35

37

13

35

37

13

35

37

12

32

≥ 75

12

7

58

12

2

17

12

4

33

12

4

33

12

3

25

  1. aTotal evaluable volunteers at any time point during the study
  2. bResponders at any time point during the study
  3. Responses for cytokines: ≥2 fold increases vs. day 0
  4. Bolded % indicate a difference ≥ 10% among the compared groups