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Table 3 Hazard ratios for the combined associations of hs-CRP and cognitive impairment with all-cause mortality (N = 1447)

From: Combined associations of hs-CRP and cognitive function with all-cause mortality among oldest-old adults in Chinese longevity areas: a prospective cohort study

Groups/HR

No. of deaths

Model 1

Model 2a

1: hs-CRP ≤ 3.0 mg/L and normal cognition

312

1

1

2: hs-CRP > 3.0 mg/L and normal cognition

117

1.80 (1.24, 2.61)

1.70 (1.13, 2.56)

3: hs-CRP ≤ 3.0 mg/L and CI

286

2.79 (1.82, 4.28)

2.39 (1.61, 3.55)

4: hs-CRP > 3.0 mg/L and CI

111

4.61 (3.16, 6.72)

3.56 (2.35, 5.38)

P for trend

< 0.001

< 0.001

  1. Model 1 adjusted for age and sex; model 2 further adjusted for drinking, smoking, marital status, regular exercise, medication, BMI, central obesity, self-reported history of hypertension, diabetes mellitus, heart disease, stroke and cerebrovascular disease, respiratory disease and cancer. CI = cognitive impairment
  2. a P for interaction< 0.01