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Table 2 T cell and B cell subsets in CMV-negative and CMV-positive individuals

From: Long-term maintenance of diphtheria-specific antibodies after booster vaccination is hampered by latent infection with Cytomegalovirus

 

CVM-negative

CMV-positive

p

mean ± SD

mean ± SD

 

CD4+

naïve

63.0 ± 12.4

52.0 ± 15.5

0.029*

central memory

36.2 ± 12.5

38.5 ± 15.3

0.605

effector memory

0.6 ± 0.4

5.3 ± 4.2

<0.0001**

TEMRA

0.7 ± 0.6

4.7 ± 5.2

<0.0001**

CD8+

naïve

42.2 ± 16.2

28.9 ± 15.4

0.024*

central memory

25.4 ± 9.7

17.9 ± 14.0

0.005**

effector memory

8.9 ± 8.8

8.4 ± 7.3

0.939

TEMRA

24.5 ± 16.7

45.7 ± 17.5

0.001**

B cells

IgM+

19.5 ± 8.6

16.8 ± 5.6

0.286

IgD+

67.7 ± 11.9

64.6 ± 12.5

0.564

IgG+

11.2 ± 8.0

11.4 ± 4.4

0.323

memory IgG

8.3 ± 6.1

8.4 ± 3.6

0.485

exhausted

9.4 ± 2.6

11.2 ± 6.8

0.862

  1. Percentage of naïve (CD45RO−CD28+), central memory (CD45RO+CD28+), effector memory: (CD45RO+CD28−), and TEMRA (CD45RO−CD28−) cells within CD3+CD4+ or CD3+CD8+ cells, respectively and of IgM+, IgD+, IgG+, memory IgG (CD27+IgG+, and exhausted (IgD−CD27−) B cells within CD20+ cells. Shown are mean values and standard deviation (SD) from 19 CMV-negative and 18 CMV-positive individuals. Differences between CMV-negative and CMV-positive groups were calculated by Mann-Whitney-U test. *p < 0.05; **p < 0.01
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Immunity & Ageing

ISSN: 1742-4933

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