Fig. 1

Age-related RAGE ligands expression difference in kidney, liver and skeletal muscle. The level of RAGE ligands including AGEs, HMGB1, and S100β in the a kidney, b liver and c skeletal muscle of young, middle-aged, old mice were validated by In-direct ELISA. Ratios represented in the graphs represent fold levels of AGEs versus young mice. **; p < 0.01 versus young mice, $$; p < 0.01 versus middle-aged mice