Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.

Skip to main content

Table 1 Singular Enrichment Analysis results from DAVID v6.7

From: Transcriptomic profiles of aging in naïve and memory CD4+ cells from mice

Gene list

Category

Term

Count

P Value

FDR

Naïve Up

GOTERM_BP_FAT

GO:0006955 ~ immune response

13

1.72E-05

0.000266

GOTERM_CC_FAT

GO:0005576 ~ extracellular region

15

4.64E-05

0.000517

KEGG_PATHWAY

mmu04060:Cytokine-cytokine receptor interaction

8

1.41E-04

0.001418

GOTERM_BP_FAT

GO:0042981 ~ regulation of apoptosis

13

3.17E-04

0.004887

Naïve Down

N/A

N/A

N/A

N/A

 

Memory Up

KEGG_PATHWAY

mmu04060:Cytokine-cytokine receptor interaction

12

1.34E-05

0.000151

GOTERM_MF_FAT

GO:0004866 ~ endopeptidase inhibitor activity

7

9.61E-05

0.001289

INTERPRO

IPR007110:Immunoglobulin-like

13

2.07E-04

0.002886

GOTERM_CC_FAT

GO:0016021 ~ integral to membrane

58

3.68E-04

0.004519

GOTERM_BP_FAT

GO:0032653 ~ regulation of interleukin-10 production

4

6.05E-04

0.00977

GOTERM_BP_FAT

GO:0002684 ~ positive regulation of immune system process

11

8.28E-04

0.01335

GOTERM_BP_FAT

GO:0051249 ~ regulation of lymphocyte activation

9

0.001606

0.025729

GOTERM_BP_FAT

GO:0050871 ~ positive regulation of B cell activation

5

0.00307

0.048641

Memory Down

N/A

N/A

N/A

N/A

N/A

  1. Lists of genes differentially expressed between young and old mice at FDR ≤0.05 in naïve and memory CD4+ T cells were used as input, with all expressed genes in naïve and memory cells used as background. Broad terms such as “signal” and “disulfide bond” were excluded. A FDR of 0.05 was used as a threshold for enriched terms. No terms were significantly enriched in down-regulated gene lists