Expression of cellular protective proteins SIRT1, HSP70 and SOD2 correlates with age and is significantly higher in NK cells of the oldest seniors

Table 1 Hematological parameters and CRP values of peripheral blood in the studied age groups

Parameters\studied group	Seniors > 85 (oldest), age: 88.4 ± 0.5 y	Seniors < 85 (old), age: 75.6 ± 0.9 y	Young, age: 21.0 ± 0.3 y	P value
Total WBC count [k/μl]	6.91 ± 0.34 *	5.92 ± 0.23 *	6.33 ± 0.23	* 0.040
Lymphocyte count [k/μl]	2.17 ± 0.12	2.12 ± 0.12	2.37 ± 0.10	0.246
Lymphocyte percentage [%]	32.22 ± 1.72	36.05 ± 1.87	37.67 ± 1.13	0.059
NK cell percentage [%]	11.06 ± 1.31	14.00 ± 1.49 ^#	9.22 ± 0.84 ^#	^# 0.034
NK cells CD56^bright [%]	4.49 ± 0.78 *	4.15 ± 0.68 ^#	7.17 ± 0.76 *^#	^# 0.004 *0.037
NK cells CD56^dim [%]	93.67 ± 0.71 *	93.58 ± 0.63 ^#	90.01 ± 0.74 *^#	^# 0.001 *0.002
CRP [mg/L]	2.16 ± 0.29 *	1.87 ± 0.27 ^#	0.81 ± 0.18 *^#	^# 0.001 *0.00003

All data are presented as means ± SEM. The same symbols ^{*, #} in one row denote statistically significant differences between the marked values

ISSN: 1742-4933