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Fig. 3 | Immunity & Ageing

Fig. 3

From: Fetal thymus graft enables recovery from age-related hearing loss and expansion of CD4-Positive T cells expressing IL-1 receptor type 2 and regulatory T Cells

Fig. 3

Therapeutic effects of the fetal thymus graft on age-related hearing loss. The auditory functions of SAMP1 mice were examined using ABR at click stimuli and pure tones of 4, 12, and 36 kHz. The development of AHL observed in untreated SAMP1 mice (*p < 0.05–0.005 between Group B aged 6 months old and Group C aged 12 months old) was canceled in thymus-grafted Group D aged 12 months old (**p < 0.01–0.0005 between Groups B and D). The thresholds of Group D showed no significant difference from those of Group A consisting of 2-month-old SAMP1 mice (p > 0.05 between Groups A and D). NS: no significance. n = 10/group (mean ± SD)

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Immunity & Ageing

ISSN: 1742-4933

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