Fig. 1

Best fit regression of PBMC gene expression with age of the patients. Dot plots represent the rel. expression of AIM2 (a), NLRP3 (b), ASC (c), CASP1 (d), CASP5 (e) and IL1B (f) normalized to the mean rel. expression of three reference genes (GAPDH, B2M, ACTB) in PBMC in relation to the age of the patient. Further details are described in materials and methods of the online data supplements