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Table 1 Number of DEGs in primary human fibroblast strains + / - rotenone

From: Hormetic effect of rotenone in primary human fibroblasts

Fibroblast

PD+/− rotenone (R)

Number of DEGs

MRC-5

PD38 − R to PD38 + R

1

PD42 − R to PD42 + R

2086

PD48 − R to PD48 + R

3527

PD52 − R to PD52 + R

319

HFF

PD22 − R to PD22 + R

1

PD26 − R to PD26 + R

4873

PD30 − R to PD30 + R

8151

PD34 − R to PD34 + R

6424

PD58 − R to PD58 + R

5726

PD74 − R to PD74 + R

60

  1. The number of differentially expressed genes at different population doublings (PDs) in MRC-5 and HFFs supplemented with low dose (0.1 μM) rotenone compared to their corresponding controls (without rotenone but with DMSO). The stringency criteria applied for retrieving the DEGs included p < 0.05 and alignment with two statistical packages DESeq [68] and edgeR [69]
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Immunity & Ageing

ISSN: 1742-4933

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