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Table 2 Cytokines production by monocytes or PBMC from elderly subjects

From: Proinflammatory profile of in vitro monocytes in the ageing is affected by lymphocytes presence

Cytokines

Cellular type

Production type

Median

Minimum

Maximum

1th quartile

3th quartile

TNF-α

Monocyte

Basal

0.0

0.0

253.1

0.0

98.4

LPS

489.8

141.6

935.2

378.8

572.2

PBMC

Basal

0.0

0.0

98.4

0.0

0.0

LPS

556.1

336.3

1425.1

433.0

694.7

IL-6

Monocyte

Basal

0.0

0.0

0.1

0.0

0.1

LPS

363.2

319.8

391.8

329.4

389.6

PBMC

Basal

0.0

0.0

0.1

0.0

0.1

LPS

321.1

246.4

489.4

283.2

405.8

IL-

Monocyte

Basal

0.3

0.0

6.8

0.0

3.7

LPS

332.5

276.1

362.3

293.3

358.3

PBMC

Basal

0.0

0.0

12.3

0.0

6.1

LPS

323.0

280.0

336.7

299.9

331.4

CXCL-8

Monocyte

Basal

59.5

9.3

213.2

11.8

158.9

LPS

202.8

191.1

219.6

193.3

214.8

PBMC

Basal

160.1

16.7

197.5

82.3

184.9

LPS

206.5

200.6

224.5

200.7

218.4

MCP-1

Monocyte

Basal

4.6

0.0

125.1

0.0

125.1

LPS

999.6

988.0

1039.2

988.0

1039.2

PBMC

Basal

314.8

85.2

362.3

85.2

362.3

LPS

994.4

948.2

1013.4

948.2

1013.4

TGF-β

Monocyte

Basal

0.0

0.0

0.1

0.0

0.1

LPS

23.3

0.0

78.6

0.0

62.6

PBMC

Basal

0.0

0.0

0.1

0.0

0.1

LPS

117.0

0.0

397.8

0.0

315.9

IL-10

Monocyte

Basal

24.6

0.0

358.6

0.0

271.2

LPS

903.4

447.2

3115.4

701.3

1044.9

PBMC

Basal

28.1

0.0

508.2

12.2

52.4

LPS

966.8

490.3

1139.2

649.8

1031.2

  1. Values showed by median, minimum, maximum, 1th and 3th quartiles obtained by descriptive statistical analysis (Statsoft Software Inc. Tulsa, Ok, USA).