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Table 2 Cytokines profile

From: Septic shock in older people: a prospective cohort study

 

Young

Elderly

Group A vs. B

Control n=36

Septic shock (group A) n=21

p-value

Control n=8

Septic shock (group B) n=8

p-value

p-value

IL-1α

31 ± 42

100 ± 82

0.000

27 ± 27

75 ± 82

0.270

0.242

IL-1β

2.50 ± 2.93

7.09 ± 7.11

0.007

1.12 ± 1.35

4.37 ± 6.98

0.480

0.148

IL-1 RA

36 ± 47

192 ± 295

0.001

31 ± 33

145 ± 292

0.114

0.317

IL-2

9.00 ± 6.74

13 ± 10

0.121

4.12 ± 2.10

9.62 ± 5.52

0.023

0.508

IL-3

2.08 ± 2.44

2.61 ± 3.33

0.849

0.62 ± 0.51

2.25 ± 2.54

0.070

0.899

IL-4

8.55 ± 10.60

32 ± 48

0.007

3.87 ± 4.91

16.00 ± 22.35

0.093

0.334

IL-5

2.19 ± 3.24

7.19 ± 9.26

0.010

0.50 ± 1.06

2.87 ± 3.44

0.082

0.208

IL-6

37 ± 63

1641 ± 3195

0.000

32 ± 39

1666 ± 3590

0.036

0.884

IL-7

11 ± 8.26

40 ± 39

0.000

5.62 ± 3.46

34.75 ± 48.70

0.002

0.393

IL-8

29 ± 25

806 ± 2819

0.000

26.25 ± 22.24

1695 ± 4602

0.016

0.354

IL-9

2.08 ± 2.37

4.52 ± 5.06

0.044

0.50 ± 1.06

4.25 ± 6.11

0.043

0.489

IL-10

12 ± 16

626 ± 2195

0.000

38 ± 78

480 ± 1079

0.012

0.575

IL-12p40

39 ± 44

111 ± 80

0.000

31 ± 34

141 ± 214

0.206

0.464

IL-12p70

7.19 ± 4.79

20.61 ± 20.09

0.002

4.50 ± 2.72

10.50 ± 8.79

0.423

0.195

IL-13

4.86 ± 6.51

14.90 ± 32.48

0.119

1.37 ± 1.06

10.87 ± 16.12

0.097

0.583

IL-15

7.38 ± 6.23

20.52 ± 25.30

0.001

4.00 ± 3.20

16.62 ± 18.92

0.011

0.558

IL-17

2.88 ± 2.43

8.66 ± 6.31

0.000

1.87 ± 1.45

6.87 ± 5.46

0.018

0.493

IFNα

67 ± 42

110 ± 58

0.000

195 ± 402

78 ± 38

0.270

0.150

IFNy

7.83 ± 4.45

40.09 ± 52.41

0.000

6.25 ± 5.67

30.87 ± 36.56

0.013

0.574

TFNα

19 ± 21

111 ± 207

0.000

23 ± 20

81 ± 102

0.016

0.770